We're Open!

310 S Dale Mabry Hwy #240, Tampa, FL 33609

4625 E Bay Dr #222, Clearwater, FL 33764

ReFissa® Topical

Solomon Cosmetic Center is proud to add ReFissa®  to our selection of medical-grade skin care products. ReFissa® contains tretinoin, a prescription-strength form of vitamin A that works deep in the skin’s cellular level to increase collagen production. Over time, fine facial wrinkles, irregular pigmentation, and rough skin diminish.

The four-step skin care program is easy to follow and only takes a few moments each day:

Step 1: Each night, gently wash your face with a mild soap or cleanser and pat dry.
Step 2: Let your face dry for 20 to 30 minutes before applying ReFissa®.
Step 3: Squeeze a pearl-sized amount (1/4” in diameter) of ReFissa® onto your finger.
Step 4: Dot ReFissa® onto cheeks, forehead, and chin. Spread evenly. Avoid the eyes and the skin around the ears, lips, and nostrils.

What Makes ReFissa® Different?

  • Available by prescription only
  • Clinically proven to be effective
  • Approved by the FDA
  • The only 0.05%-strong prescription tretinoin cream that’s fragrance-free with a moisturizing, emollient base.


ZO Skin Health, Inc. develops and delivers innovative skincare solutions that optimize skin health based on the latest advances in skin therapy technologies, unique delivery systems, bioengineered complexes and exclusive formulations. By providing comprehensive skincare programs for physicians and their patients, ZO Skin Health, Inc. bridges the gap between therapeutic treatments and daily care, allowing patients to experience continuously healthy skin regardless of their age, ethnicity or unique skin condition.

ZO® Medical Therapeutic Solutions
Products, protocols and treatments exclusively provided by skincare professionals for a wide range of skin disorders and chronic conditions.

Advanced Skin Health Solutions
Under the guidance of Dr. Zein Obagi, ZO Skin Health, Inc. has developed a wide spectrum of therapeutic treatments for everyone regardless on skin condition, age, gender or ethnicity. Based on the latest advances in skin therapy technology – biotechnology complexes and multi-therapy delivery systems – these products and programs have been optimized for your specific needs.



Exfoliating Polish

ZO Exfoliating Polish

Hydrafirm™ Eye Brightening Repair Creme

ZO Hydrafirm eye brightening repair creme

Growth Factor Serum

Growth Factor Serum

 Daily Power Defense

Daily Power Defense


Dr. Obagi’s legacy began with his initial quest to explain skin health, which he defines as skin that is naturally smooth, strong, firm, even-toned, hydrated and free of disease. His definition soon caught on with respected colleagues in the fields of dermatology and plastic surgery. This assisted physicians to achieve better treatment results after determining more appropriate solutions to a patient’s concern, rather than simply focusing on a diagnosis. His pioneering definition also included a Skin Classification System, enabling physicians to determine the best treatments and predict patient response based on an individual’s ethnicity and skin type.

Contact us